Health and Medicine
Explore Health and Medicine
Improving the Outlook for Children with Congenital Heart Disease | Dr Marta Erlandson
Congenital heart disease (CHD) is one of the most common birth defects across the globe. Although prospects and survival rates are improving, there is scant understanding or help available to get children with CHD active. Many believe physical activity is risky or outright dangerous, and as a result, children with CHD are at risk of obesity and other chronic conditions later in life. Dr Marta Erlandson from the University of Saskatchewan has aided the creation of CHAMPS, an innovative program for children with CHD, where researchers and children are learning how to manage the disorder from each other.
The Unease Modulation Model: Revolutionising Health, Stress Management and Public Policy | Dr Joseph Arpaia – Dr Judith P. Andersen
Stress is inherently prevalent in our lives and can have seriously deleterious impacts on individual health and well-being, as well as society more broadly. Dr Joseph Arpaia a psychiatrist in private practice in the USA, and colleague Dr Judith P. Andersen of the University of Toronto Mississauga in Canada, have proposed a new theoretical account of stress that has the potential to revolutionise clinical care in the fields of psychiatry and addiction, and improve well-being on a global level.
Preventing Rabies: A Deadly but Neglected Disease | Dr Joanne Maki
Rabies is transmitted from animals to humans through the bite of an infected animal, all too often with fatal consequences, particularly in the developing world. Dr Joanne Maki, Technical Director for the Veterinary Public Health Centre at Boehringer-Ingelheim Animal Health, has worked in rabies prevention for 30 years. With extensive background and experience gained in the rabies vaccine industry, Dr Maki shares her perspectives on the call to action to eliminate this deadly zoonotic disease.
Immigration, Epidemic Mortality and Demographic Recovery | Dr Pierre Galanaud
Dr Pierre Galanaud, an immunologist from Paris-Saclay University and Inserm UMR 996, analysed historical tax records to investigate the impact of epidemics on recent emigrants who experienced the 15th century plagues in Dijon, France. His research highlights the vulnerability of emigrants with low economic status to epidemic-related mortality. More broadly, his work demonstrates the important role that migrants play in population growth and demographic recovery after an epidemic has taken place. These findings are of particular relevance given the current COVID-19 pandemic.
Dream Warmer: An Innovative, Safe and Effective Complement to Skin-to-Skin Care for Neonatal Hypothermia | Dr Anne Hansen
Dr Anne Hansen is the Medical Director of the Neonatal Intensive Care Unit and Associate Chief of the Division of Newborn Medicine at Boston Children’s Hospital. With her colleagues, Dr Hansen has developed and tested a low cost, non-electrical warming mattress called the ‘Dream Warmer’ to help prevent and treat neonatal hypothermia in countries with limited medical resources. Her team has conducted extensive testing in Rwanda with results demonstrating that this medical device is safe, effective and ready for use on a wider scale.
Understanding Sudden Unexpected Infant Death: A Unique Collaboration
When a supposedly healthy infant passes away, it can be hard to understand why. Juan Lavista Ferres (Microsoft), Dr Jan-Marino Ramirez and Dr Tatiana Anderson (both from Seattle Children’s Research Institute), and Professor Edwin Mitchell (University of Auckland), form the core of a novel collaboration to conduct vital and extensive research into the risk factors and mechanisms behind sudden unexpected infant death. This unique collaboration spanning across disciplines, industries and continents, is providing the deeper understanding that is needed to prevent unnecessary infant deaths.
Return of Baird’s Tapir: Blessing or Omen? | Dr LaRoy Brandt – Maggie Singleton
The destruction of jungle and forest habitats is a serious issue threatening species across the globe. Dr LaRoy Brandt and Maggie Singleton of Lincoln Memorial University studied one such threatened species, Baird’s tapir, in Costa Rica. By identifying the tapir’s tracks and deploying remote trail cameras, the team caught rare glimpses of this threatened species, indicating a return of the native population and an increase in their numbers. The question is, however, is this increase a sign of improving habitats or a result of less favourable forces at play?
Confronting Challenges to the Uptake of Digital Healthcare | Paola Mattei
Digital healthcare promises a wealth of benefits for current healthcare systems, yet its uptake has been remarkably slow across Europe. Taking the example of the UK in particular, Paola Mattei, Associate Professor in Political Science at the University of Milan, Italy, has recently considered the explanations for the slow uptake of digital healthcare and provides a commentary on why this is the case and what challenges now need to be faced to ensure success.
Do Maternal Influences on Birthweight Influence Future Cardiometabolic Risk? | Dr Gunn-Helen Moen
Adverse environmental factors in the mother’s womb and/or during the first years of life have traditionally been thought to be responsible for an increased risk of cardiometabolic disease for children later in life. Dr Gunn-Helen Moen [MO-en] at the University of Oslo in Norway and her collaborators used sophisticated statistical and genetic techniques to identify whether there is a causal effect of environmental factors that influence intrauterine growth on future cardiometabolic risk in the child. Their results were surprising but important.
Using Machine Learning to Predict Bacterial Growth According to the Media Components | Dr Bei-Wen Ying
Bacterial growth depends on the complex interactions of a multitude of chemical components. Microbiologists have long attempted to predict bacterial growth according to culture media components, and have employed a variety of mathematical and computational models to this end. Dr Bei-Wen Ying and her colleagues at the University of Tsukuba, Japan, successfully applied machine learning to understand the contribution of media culture components to bacterial growth. Their work makes a significant contribution to growth prediction and demonstrates that machine learning can be employed in the exploration of the complex dynamics that regulate living systems.
How Cancer Cells Overcome the Obstacle of Senescence | Sebastian Igelmann
Cellular senescence [suh-NEH-Sns] is the process by which cells age and permanently stop dividing but do not die. While the process of senescence creates a barrier to tumour formation, it can still be overcome by cancer cells. Sebastian Igelmann, a PhD student supervised by group leader Dr Gerardo Ferbeyre at the University of Montreal, has identified a group of enzymes that work together to reprogramme cellular metabolism. This work provides important insight into how tumour cells may initiate proliferation and circumvent senescence. Critically, this specialist group of enzymes provides a potential therapeutic target for human cancer treatment.
The Holy Grail of Safer Opioids: Targeting Mu Opioid Receptor Splice Variants | Dr Ying-Xian Pan
Despite their numerous side effects, opioid drugs and morphine-like agents have remained a pillar in the medical management of pain. Most clinically used opioid drugs act through mu opioid receptors. Dr Ying-Xian Pan and his team from the Rutgers New Jersey Medical School, USA, studies the molecular and cellular mechanisms of mu opioid receptors and aim to develop novel strategies and opioid analgesics for better treating pain without side effects associated with traditional opiates. Efforts to find substitutes for traditional opioid drugs are helping address the opiate abuse crisis that affects many countries around the globe.
Increase The Impact Of Your Research!
Explore partnership opportunities
Unwind without the hassle. Enjoy fresh audiobooks, delivered free!