The UK-based Pregnancy Care Integrating Translational Science, Everywhere (PRECISE) Network has set up biorepositories across sub-Saharan Africa to investigate the causes of placental pregnancy complications and enhance research capacity. The project encountered several challenges relating to facilities, staffing, training, cultural barriers, procurement, shipping and sample storage which impacted project timings and budget. However, with appropriate training and infrastructure development, the researchers have shown that is possible to facilitate high-quality sample collection in this region. This important achievement provides vital encouragement in support of establishing further biorepositories in less affluent regions.

Interventions designed to improve health, including targeted drugs and medical devices, typically undergo a complex and lengthy process of development. In a collaboration between the University of Wisconsin-Madison, Cornell University, the National Institutes of Health and Case Western Reserve University in the USA, experts Dr Clara Pelfrey, Dr Linda Scholl and colleagues have designed a case study protocol to improve understanding of this process.

The inability to access land is a major cause of poverty in agricultural societies. Women, who are less likely to own, rent, buy or inherit land, are particularly affected and access to communal land may provide a vital lifeline. Dr Jozelin María Soto-Alarcón and Dr Diana Xóchitl González-Gómez set out to investigate the use of communal land in a rural community in Mexico, investigating the strategies used by a collective of women to achieve access to this critical resource.

While research into the experiences of people with autism and their families is flourishing, there remains relatively little research on the experiences of typically developing siblings, particularly those on the brink of adulthood. Ms Caitlin Calio, Masters of Teaching, and Professor Ann Higgins-D’Alessandro at Fordham University in the USA, are dedicated to overcoming this important knowledge gap to help inform both theory and the development of appropriate practical support.

Professor Zygmunt Pizlo at the University of California-Irvine has advanced degrees in both engineering and psychology. He is drawing on his extensive experience in these often disparate fields to explore how fundamentals in physics can explain how we see the world around us. His novel work extrapolating from the importance of symmetry in physics and the natural world opens up exciting possibilities for psychology and cognitive science.

Military veterans are diagnosed with posttraumatic stress disorder at a much higher rate than civilians. There is a growing interest in psychiatric assistance dog placements to help veterans cope with their symptoms, however research into their effectiveness is limited. Sarah Leighton and her colleagues from Purdue University and the University of Arizona have undertaken a review of the existing evidence surrounding these partnerships to determine their efficacy. Whilst more detailed and robust research is still needed, they found positive support for this intervention.

Most human diseases are localised in terms of their location but currently, injected or orally administered drugs are evenly distributed all over the body and thus, act indiscriminately. The targeted delivery of medication to the exact site where it is needed is a common theme in science fiction but thanks to Professor Richard Klemke and his team at the University of California San Diego’s Moores Cancer Center, this fantasy may soon become a reality.

Although human immunodeficiency virus (HIV) is still prevalent worldwide, life-saving antiretroviral drugs can now prevent an infection from progressing into acquired immunodeficiency syndrome (AIDS). Nevertheless, people who are HIV-positive are still at increased risk of developing neurological disorders and cardiovascular diseases, known as co-morbidities. Professor Michael Bukrinsky from the George Washington University in Washington DC works to understand the underlying biological mechanisms that lead to these disorders. His research has produced interesting results that demonstrate the role of altered lipid (cholesterol) homeostasis in HIV-infected cells and how this comes to pass.

Epilepsy is a chronic, long-term disease in which abnormal activity in the brain leads to repeated seizures, and it affects nearly 70 million people worldwide. The exact mechanisms behind epileptic seizures are still poorly understood. However, we do know that epilepsy can be caused by changes in the network structure of our brains and that seizures may be a result of spontaneous excessive brain synchronisation. Professor Eckehard Schöll and his Master student Moritz Gerster together with colleagues are using computer simulations to better understand the interplay of network structure and network synchronisation in epilepsy.

Epilepsy is a chronic, long-term disease in which abnormal activity in the brain leads to repeated seizures, and it affects nearly 70 million people worldwide. The exact mechanisms behind epileptic seizures are still poorly understood. However, we do know that epilepsy can be caused by changes in the network structure of our brains and that seizures may be a result of spontaneous excessive brain synchronisation. Professor Eckehard Schöll and his Master student Moritz Gerster together with colleagues are using computer simulations to better understand the interplay of network structure and network synchronisation in epilepsy.