Biology
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Dr Laura Tipton | Symbiotic Science through a Shared Language
Many scientific concepts are applicable to multiple disciplines and across spatial scales, from the microscopic to the global. As such, scientists from different disciplines must communicate effectively – through a shared scientific language – for effective collaboration and scientific advancement. With this aim, Dr Laura Tipton of Chaminade University and her colleagues from the University of Hawai’i investigate the history of ecological terminology, in order to work towards building a common lexicon that bridges ecology and microbiome science.
Dr Jennifer Botha – Analysing Bones to Gain Insight into Mammalian Evolution
It may be surprising to know, that you – and all other mammals – are technically cynodonts. The first cynodonts appeared approximately 260 million years ago as small creatures about the size of a house cat. A particular group of cynodonts evolved to become more ‘mammal-like’, eventually evolving into the first true mammals. Dr Jennifer Botha from the National Museum, Bloemfontein in South Africa studies the anatomy and life history of specimens along the cynodont–mammalian transition, to gain key insights into the origins and evolution of mammals.
Dr Zsuzsanna Balogh-Brunstad | Getting to the Root of Plant-Fungi Symbiosis
An ancient relationship between plants and fungi could help us improve forestry and agriculture, while also responding to the challenges posed by climate change. These beneficial fungi, along with their bacteria helpers, help plants to grow bigger and healthier, and survive droughts. An international team of researchers has been investigating how these fungi and bacteria increase mineral availability for Scots pine and red pine seedlings through mineral weathering.
Dr Laura Tipton | Symbiotic Science through a Shared Language
Many scientific concepts are applicable to multiple disciplines and across spatial scales, from the microscopic to the global. As such, scientists from different disciplines must communicate effectively – through a shared scientific language – for effective collaboration and scientific advancement. With this aim, Dr Laura Tipton of Chaminade University and her colleagues from the University of Hawai’i investigate the history of ecological terminology, in order to work towards building a common lexicon that bridges ecology and microbiome science.
Dr Helen Greenwood Hansma | Energy: A Clue to the Origins of Life
Energy is vital for life. It allows important functions to occur in living systems, from the molecular level to the scale of the whole organism. Dr Helen Greenwood Hansma, from the University of California in Santa Barbara, believes that the types of energy used in living cells can provide clues to help us understand the origins of life. In her recent research, she explores how mechanical energy could have driven the processes that gave rise to early life in the absence of chemical energy.
Investigating the Impact of Tannins on Gut Bacteria in Pigs
Weaning is an important time in the pig lifecycle, and changes in diet and environment can lead to unbalanced gut microbiota and pathogen colonisation. Prof. Luciana Rossi, Dr. Matteo Dell’Anno from the University of Milan, and Dr. Maria Luisa Callegari from Catholic University of Sacred Heart, have been investigating the impact on gut bacteria of adding natural compounds known as tannins to piglet food. Importantly, they found that tannins do affect the gut bacteria; with increases seen in bacteria associated with improved growth and gut health, and in particular, those that produce butyrate – a substance with proven health benefits.
Dr Christa Mulder – Understanding How Flowering Plants Respond to Climate Change
A welcome sign of a change in seasons, the year’s first flowers usher in the start of spring. Yet, as the climate warms, some flowers are blooming earlier. Since plants respond to environmental cues, such as temperature, shifts in their annual development has long been considered an effect of climate change. However, significant warming does not always lead to earlier flowering.
Effects of DNA Repair Mechanisms, Oestrogen and Environmental Chemicals on Risk for Breast Cancer | Dr Joseph Jerry
All women are exposed to oestrogen from puberty through menopause. Oestrogen is a natural hormone that is important for breast development and the maintenance of tissues in women but is also linked to an increased risk of breast cancer. As many as 1 in 8 women in the USA will be diagnosed with breast cancer over their lifetime, and the majority of these breast cancers are sensitive to oestrogen. Dr Joseph Jerry and his collaborators at the University of Massachusetts are studying the environmental exposures and genetic differences that alter the consequences of exposure to oestrogens.
Revealing How Ocean Chemistry Controlled Earth’s Ancient Atmosphere and Microbial Evolution | Dr Romain Guilbaud
Important clues buried within ancient rocks that were deposited on the ocean floor around one billion of years ago could help scientists understand the evolutionary history of life on Earth. Dr Romain Guilbaud and an international team of researchers from the UK and China analysed the chemical composition of these rocky sediments from the Huainan Basin in North China. Their findings demonstrate how changes in ocean chemistry occurring between one billion and 800 million years ago strongly limited the production of atmospheric oxygen, which is a necessary prerequisite for the planet to host complex life.
Discovering Unmapped Molecular Targets for Novel Covalent Drugs | Dr Mikail Abbasov
Covalent drugs are molecules that irreversibly bind to specific, targeted sites in the body. They work to inhibit the disease-causing functions of certain proteins by preventing them from interacting with other substances. This is a highly promising field of drug development and the focus of Dr Mikail Abbasov from Cornell University, New York, USA. By creating and utilising new technologies and through collaborative research, Dr Abbasov has mapped novel molecular targets for potential covalent drugs to treat ailments ranging from cancer to autoimmune diseases.
Understanding Why Obesity is a Risk Factor for Cancer | Dr Aliccia Bollig-Fischer
Cancer can be caused by genetic mutations or epigenetic alterations, which are changes to the way DNA is processed, rather than to the DNA itself. These changes can be brought about by obesity, and more specifically, oxidative stress and consequent reactive oxygen species. However, the molecular mechanisms by which this occurs are not well understood. Dr Aliccia Bollig-Fischer from Wayne State University School of Medicine in Michigan is studying these processes and paving the way for the development of novel cancer therapeutics.
Discovery of Neurotrophic Factor-α1 Reveals New Treatment Strategies for Stress-induced Neurodegenerative Diseases and Depression | Dr Y. Peng Loh
Stress produces numerous negative effects on the human body. Lying deep within the brain, one particularly sensitive area is the hippocampus, where chronic exposure to stress hormones can lead to the degeneration and death of neurons. Thankfully, the brain holds defence mechanisms that block some of these negative effects. Deciphering these mechanisms with the aim of better treating neurodegenerative diseases and depression is Dr Y. Peng Loh from the Eunice Kennedy Shriver National Institute of Child Health and Human Development in the USA.
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