Addressing antimalarial drug resistance in Africa to ensure patients can continue to be saved

Addressing antimalarial drug resistance in Africa to ensure patients can continue to be saved

We are pleased to be joined by Dorothy Achu, Regional Malaria Adviser, WHO African Region; Aimable Mbituyumuremyi, Director, National Malaria Control Program, Ministry of Health, Rwanda; Adam Aspinall, Senior Director, Access and Product Management, and George Jagoe, Executive Vice-President Medicines for Malaria Venture. To learn about antimalarial drug resistance in Africa to ensure patients can continue to be saved.

Dr Kerstin Kleinschmidt-Doerr | Could R399E Become a Promising Treatment for Restoring Joints and Relieving Pain in Osteoarthritis?

Dr Kerstin Kleinschmidt-Doerr | Could R399E Become a Promising Treatment for Restoring Joints and Relieving Pain in Osteoarthritis?

Osteoarthritis is a painful and progressive joint disorder that affects hundreds of millions of people worldwide. Typically, the options for treating the condition involve exercise or medication to reduce pain. However, these methods do not target the underlying structural problems in the joints of patients. Recently, researchers have uncovered a genetic susceptibility to osteoarthritis associated with a protein called GDF5, which is involved in skeletal growth and development. Alongside a team of scientists across Europe, Dr Kerstin Kleinschmidt-Doerr at Merck has explored a modified form of the GDF5 protein, named R399E, which showed effects in animal models and in-vitro experiments for treating pain and the underlying structural problems in osteoarthritis.

Dr Xiaomu Li | Understanding Diabetes: Revealing the Links Between High Blood Pressure and Insulin Resistance

Dr Xiaomu Li | Understanding Diabetes: Revealing the Links Between High Blood Pressure and Insulin Resistance

Cases of type 2 diabetes are on the rise around the world, so gaining a deeper understanding of this chronic condition is vital to ensure early diagnosis and good outcomes for patients. Dr Xiaomu Li and her colleagues at Zhongshan Hospital, Fudan University are conducting important research to understand the risk factors associated with developing type 2 diabetes. Their findings will help healthcare providers to identify patients at high risk of diabetes, enabling early diagnosis and targeted interventions to prevent the development of the condition.

Dr Millie Nakatsuka | Decoding Dizziness in the Emergency Room

Dr Millie Nakatsuka | Decoding Dizziness in the Emergency Room

Acute vestibular syndrome is one of the most common reasons people present at hospital with dizziness. The symptoms can arise from damage within the brain or the ear, and specialist medical knowledge or equipment is typically needed to determine the specific cause. Dr Nakatsuka from the University of Sydney in Australia has conducted a large-scale analysis and review of the published literature to determine whether well-trained emergency physicians can differentiate between the two causes, using a quick bedside physical examination without expensive special equipment.

Dr Youzhong Guo | Accelerating Our Understanding of Cell Membranes

Dr Youzhong Guo | Accelerating Our Understanding of Cell Membranes

Cell membranes are critical for life. Effectively extracting proteins with naturally associated lipids from cell membranes is necessary for research, but traditional methods may damage these membrane components and limit the accuracy of scientific data. Dr Youzhong Guo at Virginia Commonwealth University has recently developed a revolutionary method for extracting membrane components in the form of Native Cell Membrane Nanoparticles. His team’s exciting work advances our understanding of the structure, function and interactions of membrane proteins and lipids.