Dr Ben Jones – Key Advances in Measuring the Effect of Training in Competitive Swimmers

Dr Ben Jones – Key Advances in Measuring the Effect of Training in Competitive Swimmers

Swimming was one of the nine original Olympic sports in 1896, and to this day, remains one of the most popular competitive and recreational sports. However, methods to track the effect of training programmes and physiological changes in swimmers have lagged behind those of other sports due to difficulties caused by the aquatic environment. Dr Ben Jones and his team from the University of Essex have used a novel underwater near infrared spectrometer to monitor the effects of a training programme on muscle oxygenation in teenage swimmers.

The 2022 Prince Mahidol Award Conference: Building the World We Want

The 2022 Prince Mahidol Award Conference: Building the World We Want

Humanity is facing many challenges, ranging from COVID-19 to climate change, and from natural resource depletion to social inequity. The Prince Mahidol Award Conference is an annual event held in Bangkok, where leaders and experts meet to discuss global challenges. This year, the theme was ‘The World We Want: Actions Towards a Sustainable, Fairer and Healthier Society’.

Effects of DNA Repair Mechanisms, Oestrogen and Environmental Chemicals on Risk for Breast Cancer | Dr Joseph Jerry

Effects of DNA Repair Mechanisms, Oestrogen and Environmental Chemicals on Risk for Breast Cancer | Dr Joseph Jerry

All women are exposed to oestrogen from puberty through menopause. Oestrogen is a natural hormone that is important for breast development and the maintenance of tissues in women but is also linked to an increased risk of breast cancer. As many as 1 in 8 women in the USA will be diagnosed with breast cancer over their lifetime, and the majority of these breast cancers are sensitive to oestrogen. Dr Joseph Jerry and his collaborators at the University of Massachusetts are studying the environmental exposures and genetic differences that alter the consequences of exposure to oestrogens.

Does Mechanical Ventilation Cause Further Brain Trauma? | Dr Thiago Bassi

Does Mechanical Ventilation Cause Further Brain Trauma? | Dr Thiago Bassi

Mechanical ventilation is a medical treatment that artificially enables the body to breathe. Despite being a potentially life-saving intervention, there are concerns it can cause damage to vital organs, such as the brain and lungs. Dr Thiago Bassi from Simon Fraser University in Canada, has undertaken a review of published studies in this field. His findings indicate a potential link between ventilator usage and cognitive impairment whilst highlighting the need for further research.

Discovering Unmapped Molecular Targets for Novel Covalent Drugs | Dr Mikail Abbasov

Discovering Unmapped Molecular Targets for Novel Covalent Drugs | Dr Mikail Abbasov

Covalent drugs are molecules that irreversibly bind to specific, targeted sites in the body. They work to inhibit the disease-causing functions of certain proteins by preventing them from interacting with other substances. This is a highly promising field of drug development and the focus of Dr Mikail Abbasov from Cornell University, New York, USA. By creating and utilising new technologies and through collaborative research, Dr Abbasov has mapped novel molecular targets for potential covalent drugs to treat ailments ranging from cancer to autoimmune diseases.

Understanding Why Obesity is a Risk Factor for Cancer | Dr Aliccia Bollig-Fischer

Understanding Why Obesity is a Risk Factor for Cancer | Dr Aliccia Bollig-Fischer

Cancer can be caused by genetic mutations or epigenetic alterations, which are changes to the way DNA is processed, rather than to the DNA itself. These changes can be brought about by obesity, and more specifically, oxidative stress and consequent reactive oxygen species. However, the molecular mechanisms by which this occurs are not well understood. Dr Aliccia Bollig-Fischer from Wayne State University School of Medicine in Michigan is studying these processes and paving the way for the development of novel cancer therapeutics.