Killers and Builders: The Diverse Roles of Our Immune System – Dr Luca Parisi, University of Milan
Original Article Reference:
This SciPod is a summary of the paper ‘Macrophage polarization in chronic inflammatory diseases: killers or builders’, published in the Journal of Immunology Research, a Hindawi journal. https://doi.org/10.1155/2018/8917804
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About this episode
Immune cells known as macrophages defend the body from infections by killing invading microbes. However, they are also capable of repairing and remodelling tissue after infection or injury. The balance of ‘killing’ and ‘building’ macrophages is carefully controlled in the body, but can be skewed at sites of chronic inflammation, such as tumours. In a recent review, Dr Luca Parisi and his colleagues at the University of Milan and the University of Insubria in Italy, examine the role of these versatile immune cells in chronic disease.
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