Killers and Builders: The Diverse Roles of Our Immune System – Dr Luca Parisi, University of Milan

Nov 5, 2019 | biology, health and medicine

 Original Article Reference:

This SciPod is a summary of the paper ‘Macrophage polarization in chronic inflammatory diseases: killers or builders’, published in the Journal of Immunology Research, a Hindawi journal. https://doi.org/10.1155/2018/8917804

About this episode

Immune cells known as macrophages  defend the body from infections by killing invading microbes. However, they are also capable of repairing and remodelling tissue after infection or injury. The balance of ‘killing’ and ‘building’ macrophages is carefully controlled in the body, but can be skewed at sites of chronic inflammation, such as tumours. In a recent review, Dr Luca Parisi and his colleagues at the University of Milan and the University of Insubria in Italy, examine the role of these versatile immune cells in chronic disease.



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