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About this episode

Our intestines contain millions of bacteria, known as our microbiota, which secrete compounds and play a key role in keeping us healthy. These bacteria don’t just affect the health of our digestive system, they can influence organs as far away as the brain. Dr Francesca Ronchi at Charité Universitätsmedizin in Berlin is determining the role of the microbiota in the prevention and development of neurological disorders.

Original Article Reference

This SciPod is a summary of the papers ‘The Gut-Brain Axis: How Microbiota and Host Inflammasome Influence Brain Physiology and Pathology’, from Frontiers in Immunology, DOI https://doi.org/10.3389/fimmu.2020.604179, and ‘Experimental priming of encephalitogenic Th1/Th17 cells requires pertussis toxin-driven IL-1b production by myeloid cells’, from Nature Communications, DOI: https://doi.org/10.1038/ncomms11541

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