Audiobook

Jun 21, 2024 | health and medicine

About this episode

Many diseases become more likely to emerge as we age, with metabolic disorders such as diabetes, and neurodegenerative conditions, such as Alzheimer’s disease, representing two frequent manifestations of poor health in old age. While many age-related diseases present very differently, many share common underlying mechanisms. These include inflammation, a build-up of reactive oxygen molecules that can damage cellular components, and a lack of sensitivity to insulin. Treatments that can effectively target these mechanisms could have transformational effects on the age-related diseases that are fueled by them, including potentially preventing such diseases from developing in the first place. Prof. Christian Bréchot and colleagues at The Healthy Aging Company have developed a drug candidate: ALF5755, the pharmacological name of a protein called Hepatocarcinoma-Intestine-Pancreas, or HIP for short, also named Reg3A, that has shown exciting evidence of effectiveness on the cognitive disorders which occur during Alzheimer’s disease and the peripheral nerve damage that often occurs in diabetes, which is called diabetic neuropathy. More

Contact

For further information, you can connect with Prof. Christian Bréchot at cbrechot@usf.edu

This work is licensed under a Creative Commons Attribution 4.0 International LicenseCreative Commons License

What does this mean?

Share: You can copy and redistribute the material in any medium or format

Adapt: You can change, and build upon the material for any purpose, even commercially.

Credit: You must give appropriate credit, provide a link to the license, and indicate if changes were made.

Increase the impact of your research!

More episodes

Dr Nina Gmeiner | 21st Century Trends in Property Regimes: Progressive Commons

The ownership of goods, including both material objects and immaterial goods such as intellectual property, is defined...

Dr Selina Våge | Modelling Microbes to Understand Ecosystem Dynamics and Infectious Diseases

Our brain’s network structure consists of many interconnected regions, each containing billions of neurons. Many...

Professor Eckehard Schöll | Understanding Spontaneous Synchronisation in Epileptic Seizures

Our brain’s network structure consists of many interconnected regions, each containing billions of neurons. Many...

Taher Saif | Dr Andrew Holle – Mechanobiology – Exploring the Mechanics of Cell Behaviour

Extracellular biophysical cues have a profound influence on a wide range of cell behaviors, including growth,...

Dr Stella Laletas | How High-conflict Divorce Can Impact Children: Understanding the Perspective of Teachers

Divorce is commonplace but can have negative impacts on the cognitive, emotional, social and psychological development...

Professor Samantha Punch | Benefits of Bridge: The Partnership Mindsport

Bridge is a popular card game played socially and competitively by millions of people throughout the world. Each game...