Establishing a Positive Control for CD4 Cells: A Vital Addition to the Research Toolkit

Mar 16, 2022 | health and medicine

Original Article Reference

This SciPod is a summary of the paper ‘A Positive Control for Detection of Functional CD4 T Cells in PBMC: The CPI Pool’, published in the journal Cells. https://doi.org/10.3390/cells6040047

About this episode

Measurement of CD4 T cell-mediated immunity requires functional tests to be conducted with viable peripheral blood mononuclear cells, PBMC. Recently, scientists at CTL successfully developed a positive control that not only verifies the functionality of CD4 T cells in PBMC, but also that the antigen-presenting cell compartment is unimpaired in the test sample as well.

 

 

 

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