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About this episode
The greatest challenge for ageing populations is that vaccines can be less protective for the elderly due to the age-related decline of the immune system. This means that improving the efficacy of vaccines in the ageing population is crucial to public health. Dr Lei Jin and colleagues from the University of Florida set out to develop a novel strategy to directly address this key issue.
Original Article Reference
This SciPod is a summary of the paper ‘New MoDC-Targeting TNF Fusion Proteins Enhance Cyclic Di-GMP Vaccine Adjuvanticity in Middle-Aged and Aged Mice’, from Frontiers in Immunology. DOI: https://doi.org/10.3389/fimmu.2020.01674.
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