A Personalised Mathematical Model for Anaemia in Patients with Chronic Kidney Disease – Dr Doris H. Fuertinger, Fresenius Medical Care

Nov 24, 2020 | biology, health and medicine, trending

Original Article Reference

This SciPod is a summary of the paper ‘Prediction of haemoglobin levels in individual hemodialysis patients by means of a mathematical model of erythropoesis’, from the open access journal PLOS ONE: https://doi.org/10.1371/journal.pone.0195918

About this episode

Individuals with chronic kidney disease commonly also suffer from renal anaemia. Renal anaemia, a condition in which individuals lack enough red blood cells to adequately supply oxygen to the tissue, can have many underlying causes. Treatment is based on hormones that stimulate the production of red blood cells but this has varying outcomes and it is difficult to estimate the effects treatment will have on a specific patient. Dr Doris H. Fuertinger at Fresenius Medical Care Deutschland is using a mathematical model to predict the causes of renal anaemia and to guide treatment for individual patients.

 

 

 

This work is licensed under a Creative Commons Attribution 4.0 International LicenseCreative Commons License

What does this mean?

Share: You can copy and redistribute the material in any medium or format

Adapt: You can change, and build upon the material for any purpose, even commercially.

Credit: You must give appropriate credit, provide a link to the license, and indicate if changes were made.

Related episodes

Dr. Archana Thakur | A Novel Immunotherapy Approach to Treat Solid Tumors

Dr. Archana Thakur | A Novel Immunotherapy Approach to Treat Solid Tumors

Developing therapies to effectively treat cancerous tumors is challenging, due to the hostility of the tumor microenvironment and the potential to unintentionally damage surrounding tissues. Infusions of immune cells can improve immune function and assist the body in fighting disease, although this approach increases the risk of inducing dangerous inflammatory responses. Dr. Archana Thakur and her colleagues at the Universities of Virginia and Pennsylvania have engineered a pioneering immunotherapy system that precisely targets cancerous cells. This new immunotherapy poses minimal risk of adverse reactions, and can be used against a wide range of tumor types.

Dr Eleanor Wilson | Breath by Breath: Decision-Making in the Final Stages of Motor Neurone Disease

Dr Eleanor Wilson | Breath by Breath: Decision-Making in the Final Stages of Motor Neurone Disease

Motor neurone disease is a currently incurable and progressive neurological disorder that severely impacts muscle function. As the disease progresses, individuals with motor neurone disease experience significant difficulties in movement, speech, swallowing, and breathing. Home mechanical ventilation can be used to support breathing and improve the quality of life. However, while this can alleviate symptoms and extend survival, it does not stop disease progression, and patients and caregivers must confront difficult decisions in their treatment journey. In a new UK study, Dr Eleanor Wilson of the University of Nottingham and colleagues have explored end-of-life decision-making in motor neurone disease patients using home mechanical ventilation.

Dr. Christopher Buck | Expanding Our Knowledge of Viral Evolution

Dr. Christopher Buck | Expanding Our Knowledge of Viral Evolution

Vitamin D has been studied as a treatment for a large number of diseases and conditions, from cancer to autism to COVID-19. However, its mode of action is not completely understood. Professor Ralf Herwig carries out his research at HG Pharma GmbH (Austria) and Ulster University (UK). His vital work explores the role of vitamin D in the body with a view to unlocking its potential as a treatment for a variety of health conditions involving the immune system.

Increase the impact of your research

• Good science communication helps people make informed decisions and motivates them to take appropriate and affirmative action.
• Good science communication encourages everyday people to be scientifically literate so that they can analyse the integrity and legitimacy of information.
• Good science communication encourages people into STEM-related fields of study and employment.
• Good public science communication fosters a community around research that includes both members of the public, policymakers and scientists.
• In a recent survey, 75% of people suggested they would prefer to listen to an interesting story than read it.

Step 1 Upload your science paper

Step 2 SciPod script written

Step 3 Voice audio recorded

Step 4 SciPod published