Professor Michael Bukrinsky at George Washington University in Washington DC is working with scientists across the globe to elucidate the molecular mechanisms behind the comorbidities associated with human immunodeficiency virus so that they can be targeted with therapies.
Professor Michael Bukrinsky at George Washington University in Washington DC is working with scientists across the globe to elucidate the molecular mechanisms behind the comorbidities associated with human immunodeficiency virus so that they can be targeted with therapies.
Shigellosis is an infection of the Shigella bacteria with over 164 million cases each year leading to 1.1 million deaths. The ever-increasing antibiotic resistance of the bacteria means we need alternatives or supplements to existing antibiotics. Dr Kristin Parent from Michigan State University is working on exciting, collaborative projects hunting for bacteriophages to be used in novel therapeutics.
Psychiatric assistance dogs trained to help with mental health symptoms have become increasingly popular as a complementary intervention for posttraumatic stress disorder (PTSD). Sarah Leighton and her colleagues from Purdue University and the University of Arizona in the USA are exploring the effectiveness of psychiatric assistance dog partnerships for military veterans with PTSD.
Trypanosomes are single-celled parasites that cause life-threatening diseases in humans, domestic livestock and wild animals. In sub-Saharan Africa, infection with a species called Trypanosoma brucei or T.brucei causes African sleeping sickness, which results in organ failure and eventually fatal coma if left untreated. There are limited diagnostic tests and treatments available and much of trypanosome biology remains undiscovered.
Covalent drugs are molecules that irreversibly bind to specific, targeted sites in the body. They work to inhibit the disease-causing functions of certain proteins by preventing them from interacting with other substances. One well-known example is the antibiotic, Penicillin.