Sphingolipids Fats that Protect the Heart – Dr Annarita Di Lorenzo, Cornell University

health and medicine

Despite current therapies, cardiovascular disease is a leading cause of death worldwide, suggesting that alternative drug targets are urgently needed to preserve cardiovascular health. Sphingolipids – a class of biologically active molecules and components of cell membranes – are a potential target, but how their synthesis is regulated in cardiac disease remains an elusive mystery. Dr Annarita Di Lorenzo and her group at Weill Cornell Medicine have begun to elucidate the molecular mechanisms regulating this pathway, which may lead to novel therapeutic treatment of cardiovascular diseases.

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